Sometimes adulticides are required when control is difficult to achieve. In some cases, even after applying other treatments, or an exceptional level of control is needed, possibly because of pest pressure, the application to resting, landing or just contact surfaces is a critical adjunct or possibly even a stand-alone treatment. In some situations other control mechanisms cannot be tolerated by the individuals affected or can have an adverse effect on non-target species. Occasionally, spraying or fogging can’t work, and or there may not be enough time for trapping to deliver the outcome needed. In yet other situations where the most complete control is required and there is an extremely low tolerance for mosquito bites, this strategy can be combined with misting, larviciding, trapping and time-release sequential aerosols .